Based in Central London’s world renowned Harley Street district

Polynucleotides

Regenerate your skin from within using polynucleotide injections. This advanced treatment stimulates your body's natural collagen and elastin production for firmer, more radiant skin.

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Bio-Regenerative Skin Treatment

Polynucleotides are one of the most exciting advances in regenerative aesthetics. These injectable treatments contain purified DNA fragments derived from salmon, chosen for their remarkable compatibility with human tissue. Unlike dermal fillers that add volume, polynucleotides work at a cellular level to repair, hydrate, and strengthen your skin from within.

When injected, polynucleotides activate fibroblasts, the cells responsible for producing collagen and elastin. Research shows they can increase collagen production by up to 47% within 23 days, resulting in a thicker, healthier skin structure. They also reduce inflammation through their antioxidant properties, improve hydration by binding to water molecules, and promote cellular repair and regeneration.

Polynucleotides are particularly effective for treating the delicate under-eye area, where traditional fillers can look unnatural. They’re also excellent for fine lines around the mouth, crepey neck skin, and overall facial rejuvenation. The treatment can be used on the face, neck, décolletage, and hands. Many practitioners recommend polynucleotides as a preparatory treatment before laser procedures or as a complement to anti-wrinkle injections and dermal fillers.

Results develop gradually over two to eight weeks as your skin responds to the treatment, with improvements continuing over several months. Most patients benefit from a course of two to three sessions spaced four to six weeks apart, with effects lasting six to twelve months. This treatment is not suitable for those with fish allergies, vegans, or anyone who is pregnant or breastfeeding.

Why choose us?

Medical-Grade Products

We use only premium polynucleotide products that undergo rigorous purification processes. Higher purity means better results and reduced risk of adverse reactions. Our practitioners select the most appropriate product for your specific concerns and treatment area.

Experienced Aesthetics Team

Our aesthetics practitioner Morgan Araka combines pharmaceutical expertise with advanced injection techniques. With a Masters in Pharmacy and specialist aesthetics training, she understands both the science behind polynucleotides and the artistry required for natural-looking results.

Personalised Treatment Plans

Every patient's skin is different. During your consultation, we assess your skin condition, discuss your goals, and create a tailored treatment plan. We may recommend polynucleotides alone or in combination with other treatments to achieve optimal results for your individual concerns.

FAQs

Dermal fillers add volume to specific areas for immediate results, while polynucleotides focus on improving skin quality at a cellular level. They stimulate your body’s natural collagen and elastin production rather than filling spaces. Results develop gradually but create genuine improvement in skin health, texture, and firmness. The two treatments work beautifully together when combined.

Polynucleotides are versatile and can treat the face, under-eye area, neck, décolletage, and hands. They’re particularly effective for the delicate under-eye area where traditional fillers can look unnatural, fine lines around the mouth, and crepey or lax skin on the neck. They can also improve the appearance of acne scars and stretch marks.

Most patients achieve optimal results with a course of two to three treatments spaced four to six weeks apart. Some patients with more significant concerns may benefit from additional sessions. After completing the initial course, maintenance treatments every six to twelve months help sustain results.

Unlike fillers that show immediate results, polynucleotides work by stimulating your body’s natural processes. You may notice initial improvements within two to three weeks, with results continuing to develop over two to three months as collagen production increases. The gradual improvement means results look natural rather than sudden.

Downtime is minimal. You may experience some redness, mild swelling, or small bruises at injection sites, which typically settle within a couple of days. Most patients return to normal activities immediately after treatment. We advise avoiding intense exercise, alcohol, and excessive heat for 24 hours following your appointment.